Our advantage
Leading technical platform
In the field of biopharmaceuticals, the company has a comprehensive biotechnology platform, mainly as follows:
- Protein evolution platform: protein directed evolution, protein engineering design based on AI/crystal structure.
- Efficient cell expression technology: based on promoter modification, fusion protein and target protein matching research and AI predicted expression research.
- Protein variant and isoform technology: based on complex proteins, multi-disulfide bond protein/enzyme variant oxidative reduction conditions and molecular companion multi-system research.
- Large-scale production platform: development of complex processes on a scale of more than 1000L, large-scale process amplification and production platform technical capabilities.
- These platforms can not only play their advantages in the field of drugs, but also play a strong driving role in the industrial protein production. At the same time, the company has also built a platform for the optimization of the prescription process for biological similar drugs and the development and evaluation of the prescription of biological new drugs. Based on the above platforms, the company can undertake the research and development and process optimization of various microorganism-expressed proteins and peptide drugs. It can also provide a variety of high-end industrial products based on this drug platform.
The industrial product platforms are as follows：
- Efficient prokaryotic cell expression platform, mammalian cell expression platform, insect cell expression platform, yeast cell expression platform.
Rich research and production experience
The company’s upstream and downstream process development team has accumulated rich experience in both pharmaceuticals and industrial products through years of technological accumulation. It has mature expression research and technical platforms, mature protein purification preparation platforms, and mature protein structure-function mechanism research platforms. In particular, in the field of high-end industrial protein products, the company has long been committed to optimizing production processes, improving product quality, protein activity and yield research, using raw materials and technologies suitable for large-scale production, providing stable downstream processes and quality research and document system construction suitable for pharmaceutical process development needs. Our products and services include monoclonal antibodies, recombinant proteins, fusion proteins, cytokines and growth factor protein drugs and industrial products purification and services, including but not limited to the following:
- Development of different host expression platforms (E. coli, mammalian cells and Bacillus subtilis);
- Development and optimization of chromatographic purification processes (affinity chromatography, ion exchange chromatography, hydrophobic chromatography, mixed mode chromatography);
- Protein CMC quality evaluation system that meets the requirements of biological raw materials and stable activity and purity output protein products;
- Technology transfer at pilot scale and 100L level;
- Protein activity analysis and quality platform capability that meets GMP requirements.
Company culture
Dedicated to the development of diabetes biopharmaceuticals
Innovation, self-motivation, teamwork, win-win